England head coach Clive Woodward announced that England and NEC Harlequins centre Will Greenwood is flying home to the UK this on compassionate grounds.
Woodward said: "Will is flying home for a week in order to be with his wife Caro, who is experiencing difficulties with her second pregnancy.
On behalf of the squad, we would appreciate it if Will and Caro could be given complete privacy at this time.
"I will not be flying out any direct replacements for Will or bringing
anybody out on standby as we have sufficient cover in the squad. Will is expected to return on October 25 to prepare for the Uruguay fixture.
"We are formally notifying the Rugby World Cup tomorrow morning (Sunday) and had planned to make the announcement on Sunday afternoon.
"However, due to a leak to an English Sunday newspaper, the England management is making the announcement earlier than expected."