In the front row, James Hayter starts at hooker in place of the injured Tani Fuga, who strained knee ligaments in the defeat to the Irish at Twickenham.

In the back row, summer signing Maama Molitika starts on the blindside flank ahead of Ace Tiatia, who is amongst the replacements. Luke Sherriff starts on the open side flank and captain Andre Vos moves to number eight, with Kai Horstmann dropping to the bench.

Tony Diprose and George Harder have recovered from a dislocated thumb and a knee injury respectively, and are both amongst the replacements.

"We let ourselves down against London Irish last weekend and are very keen to make sure we put in a much improved performance this Saturday," said Mark Evans, NEC Harlequins Chief Executive. "Our failure to take our chances proved very costly at Twickenham and we can't afford to make similar mistakes against Northampton."

"However, Northampton look set to be one of the leading contenders for the title this season and played very well in their victory over Bath. We know it will be a very tough contest on Saturday, but it is one we are really looking forward to."

The full team is as follows:

15. Gavin Duffy
14. Ugo Monye
13. Will Greenwood
12. Mel Deane
11. Simon Keogh
10. Andy Dunne
9. Steve So'oialo
1. Mike Worsley
2. James Hayter
3. Jon Dawson
4. Karl Rudzki
5. Simon Miall
6. Maama Molitika
7. Luke Sherriff
8. Andre Vos (Capt.)

Replacements:
16. Ace Tiatia
17. Ceri Jones
18. Roy Winters
19. Kai Horstmann
20. Tony Diprose
21. Jeremy Staunton
22. George Harder

*NB - There are still tickets available for Saturday's game and can be purchased by calling the Quins ticketline on 0871 871 8877, or online by clicking here.