Will Greenwood returns from international duty and takes his place in the centre alongside Dafydd James. The England international replaces Mel Deane, who drops to the replacements bench and where he takes the place of Ugo Monye, as he is away with the England Sevens team in Dubai.

Lock forward Simon Maling is not registered to play in the group stages of the Heineken Cup, so Karl Rudzki comes in to take his place on the bench.

"Realistically, we need two victories from the back-to-back games against the Ospreys if we are to stay in contention of reaching the knockout stages," said Mark Evans, NEC Harlequins Chief Executive. "However, the same can be said about the Ospreys who, like ourselves, go into Sunday's contest looking for their first win in the competition."

"It will be a genuine cup tie, with the winner staying alive in the tournament for another week and the other facing the prospect of effectively exiting the competition. Having won three games in a row, there is a renewed confidence within the team and a belief that we can get the result we require on Sunday."

The full team is as follows:

15. Tom Williams
14. George Harder
13. Will Greenwood
12. Dafydd James
11. Simon Keogh
10. Jeremy Staunton
9. Steve So'oialo
1. Mike Worsley
2. Tani Fuga
3. Ceri Jones
4. Roy Winters
5. Simon Miall
6. Nick Easter
7. Andre Vos (Capt.)
8. Tony Diprose

Replacements:
16. James Hayter
17. Jon Dawson
18. Karl Rudzki
19. Luke Sherriff
20. Andy Dunne
21. Mel Deane
22. Gavin Duffy