In the back division, George Harder misses out due to a shoulder injury so Dafydd James switches to the right wing, with Mel Deane coming in to partner Will Greenwood in the midfield. Jeremy Staunton has recovered from a knee injury and starts at fly half ahead of Adrian Jarvis, who drops to the bench.

In the pack, Mike Worsley returns from a back injury and starts in the front row at loosehead prop, with Ceri Jones taking over from Maurice Fitz Gerald on the tighthead. Simon Maling starts his first game for Quins since joining the club in November, taking the place of Simon Miall in the second row.

Having been rested last weekend, Tony Diprose returns to the back row at number eight, with captain Andre Vos reverting to the openside flank where he replaces Luke Sherriff.

The full team is as follows:

15. Tom Williams
14. Dafydd James
13. Will Greenwood
12. Mel Deane
11. Simon Keogh
10. Jeremy Staunton
9. Steve So'oialo
1. Mike Worsley
2. Tani Fuga
3. Ceri Jones
4. Roy Winters
5. Simon Maling
6. Nick Easter
7. Andre Vos (Capt.)
8. Tony Diprose

Replacements:
16. Ace Tiatia
17. Jon Dawson
18. Maurice Fitz Gerald
19. Simon Miall
20. Luke Sherriff
21. Adrian Jarvis
22. Gavin Duffy