With Will Greenwood away on international duty, Mel Deane returns to the midfield and partners Dafydd James in the centre. It will be Deane's first start since the game against Northampton Saints on 11th September, when he suffered a knee injury that kept him out of action for five weeks.

His place on the bench is taken by Ugo Monye, who has recovered from a calf strain that has forced him to miss the last four games.

Also amongst the replacements is Quins latest signing Simon Maling, though the clubs other new recruit Geo Cronje wasn't available for selection due to a knee injury.

"Clearly, it is extremely disappointing and frustrating for all connected with the club that our performances in recent weeks have not been rewarded with more than a draw against Castres in the Heineken Cup and three bonus points in the Zurich Premiership for narrow defeats against Gloucester, Leicester Tigers and London Wasps," said Mark Evans, NEC Harlequins Chief Executive.

"Saracens is the first of three hugely important league fixtures in November, the outcome of which will go a long way to shaping the rest of our Premiership campaign. Making the most of home advantage is essential both tomorrow and against Leeds Tykes in a fortnight's time (Sunday 28th November)."

The full team is as follows:

15. Tom Williams
14. George Harder
13. Dafydd James
12. Mel Deane
11. Simon Keogh
10. Jeremy Staunton
9. Steve So'oialo
1. Mike Worsley
2. Tani Fuga
3. Ceri Jones
4. Roy Winters
5. Simon Miall
6. Nick Easter
7. Andre Vos (Capt.)
8. Tony Diprose

Replacements:
16. James Hayter
17. Jon Dawson
18. Simon Maling
19. Luke Sherriff
20. Andy Dunne
21. Ugo Monye
22. Gavin Duffy