Mayhew will be joined with Kyle Sinckler and Rob Buchanan in the front row, while George Merrick and Tomas Vallejos complete the front five. Captain, Will Skinner will be joined by Luke Wallace and Joe Trayfoot in the back row.

With Casson brought into the centre, Ben Urdapilleta moves to full-back. Miles Mantella starts on the wing with Tom Williams occupying the other wing. Matt Hopper completes the backline which sees Care and Rory Clegg as half backs.

Jordan Burns (Epsom College and Harlequins EPDG) provides cover at both scrum half and wing, with Richard Bolt and Charlie Walker completing the backs replacements.

In the forwards, Tom Bristow (Dorking) and Chris Brooker provide front row options, while Sam Twomey and Charlie Matthews complete the forward replacements.

Having narrowly lost to Saracens Storm last weekend, Harlequins A will look to get their first win of the season in front of a home crowd at The Stoop.

Admission is free for season ticket holders. Non-season ticket holders can purchase tickets on the gate for £5. Gates open 6.30pm for a 7.30pm kick off.

Quins team to face Gloucester United:

15. Benjamin Urdapilletta 14. Tom Williams 13. Matt Hopper 12. Tom Casson 11. Miles Mantella 10. Rory Clegg 9. Danny Care 1. Nick Mayhew 2. Rob Buchanan 3. Kyle Sinckler 4. George Merrick 5. Tomas Vallejos 6. Luke Wallace 7. Will Skinner (C) 8. Joe Trayfoot

Replacements: 16. Chris Brooker 17. Tom Bristow 18. 19. Sam Twomey 20. Charlie Matthews 21. Richard Bolt 22. Charlie Walker 23. Jordan Burns

Gloucester United Team:

15 Gareth Knox (Clifton); 14 James Simpson-Daniel, 13 Robbie Winchle (Cinderford), 12 Callum McBurnie (Moseley), 11 Ian Clark; 10 Ryan Mills, 9 Dan Robson; 1 Yann Thomas, 2 Mati Cortese, 3 Shaun Knight; 4 Will Graulich, 5 Dave Markham; 6 Brett Deacon (capt), 7 Matt Cox, 8 Gareth Evans

Replacements:16 Koree Britton, 17 Tom Heard, 18 Henry Sandys (Hartpury), 19 Rob Langley, 20 Ollie Robinson, 21 Nick Runciman, 22 Ryan Brend, 23 Reuben Haile (Taunton)

Harlequins' first team squad return to The Stoop on Friday night, when they face Connacht in the Heineken Cup. Tickets are still available and can be purchased online by clicking here, or by calling the ticket office on 0871 527 1315