Mike Brown is released from England duty and comes back into the side at full back alongside Ugo Monye. Monye sat out last week following an injury while playing for the England Saxons. They start in the back three along with Tom Williams.

George Lowe starts in the Aviva Premiership for the first time since his injury in November. Lowe will partner Tom Casson in the centre, while Nick Evans and Danny Care continue their half back partnership.

The front row sees Joe Marler returning from England duty, with Chris Brooker starting in a continuation of the rotation policy at hooker. The remainder of the pack is unchanged from London Irish last week. James Johnston forms the cornerstone of the scrum, with Ollie Kohn and George Robson in the second row axis. Tom Guest, Luke Wallace and Nick Easter complete the back row.

Joe Gray, Mark Lambert and Tim Fairbrother will look to impact from the bench in the front row, with Tomas Vallejos and Will Skinner covering the back five. Karl Dickson and Rory Clegg provide cover at half back as Ross Chisholm covers the remainder of the backline.

Quins team to face Worcester Warriors

15. Mike Brown
14. Tom Williams
13. George Lowe
12. Tom Casson
11. Ugo Monye
10. Nick Evans
9. Danny Care

1. Joe Marler
2. Chris Brooker
3. James Johnston
4. Ollie Kohn
5. George Robson (C)
6. Tom Guest
7. Luke Wallace
8. Nick Easter

16. Joe Gray
17. Mark Lambert
18. Tim Fairbrother
19. Tomas Vallejos
20. Will Skinner
21. Karl Dickson
22. Rory Clegg
23. Ross Chisholm