With just one change to the back line, Danny Care returns to the starting line-up with Karl Dickson named among the replacements.

There are two changes to the pack that beat London Welsh last week as Charlie Matthews joins George Robson in the second row.

Nick Easter returns to start at number 8 as Tom Guest moves to the blindside flanker position.

Among the replacements, Peter Browne and Rory Clegg will look to make their first appearance of the season, with Maurie Fa'asavalu covering the back-row.

Harlequins Team to face Sale Sharks

15 Mike Brown
14 Tom Williams
13 George Lowe
12 Jordan Turner-Hall
11 Ugo Monye
10 Nick Evans
9 Danny Care

1 Joe Marler
2 Joe Gray
3 James Johnston
4 Charlie Matthews
5 George Robson
6 Tom Guest
7 Chris Robshaw (C)
8 Nick Easter

Replacements

16 Rob Buchanan
17 Darryl Marfo
18 Will Collier
19 Peter Browne
20 Maurie Fa'asavalu
21 Karl Dickson
22 Rory Clegg
23 Matt Hopper