Mike Brown and Danny Care return from international duty with England to start at full-back and scrum-half respectively, while Matt Hopper is joined in the centres by Tom Casson.

Number 8, Nick Easter continues as captain in a forward pack that is unchanged from last week's match with Worcester Warriors.

Ugo Monye and Ben Botica return from injury and are named among the replacements. Darryl Marfo and Joe Trayfoot, who replaces the injured Tom Guest, will look to make their Heineken Cup debuts.

Harlequins Team

15. Mike Brown
14. Tom Williams
13. Matt Hopper
12. Tom Casson
11. Sam Smith
10. Nick Evans
9. Danny Care

1. Mark Lambert
2. Joe Gray
3. James Johnston
4. Olly Kohn
5. George Robson
6. Maurie Fa'asavalu
7. Luke Walalce
8. Nick Easter

16. Rob Buchanan
17. Darryl Marfo
18. Will Collier
19. Charlie Matthews
20. Joe Trayfoot
21. Karl Dickson
22. Ben Botica
23. Ugo Monye